Nucynta (tapentadol)

Nucynta (tapentadol) is a good option to treat pain and may be more tolerable than other opioid pain medications.




  • In studies, Nucynta (tapentadol) was effective in treating certain kinds of pain.
  • May not cause as much nausea and constipation as other opioid pain medicines.
  • You can take Nucynta (tapentadol) with or without food; it makes no difference.


  • If you’re taking the immediate release form of Nucynta (tapentadol), you may need to take it up to 6 times a day to relieve your pain.
  • You may not be able to drive or operate heavy machinery, until you know how Nucynta (tapentadol) affects you.
  • Nucynta (tapentadol) may increase the chance of seizures.
  • Nucynta (tapentadol) is more expensive than most other opioid pain medications. A generic option of Nucynta (tapentadol) is not available.
How it works

Nucynta (tapentadol) is an opioid medicine that works in the brain to lower the amount of pain you feel.

Quick facts about Nucynta
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Pain
  • Nerve pain from diabetes
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